An worldwide innovative solution for dry mouth
Xerostomia (Dry mouth)?
xerostomia (Dry mouth), commonly known as dry mouth, is a sensation that is normally perceived when the flow of saliva is reduced to approximately half its normal amount.
Among other symptoms, dry mouth causes difficulty chewing, swallowing and speaking. In addition, it predisposes to bad breath, tooth decay, tooth infections or ulcers.
Severe xerostomia (Dry mouth) is usually caused by adverse effects to treatments or medications, such as radiotherapy and chemotherapy in cancer patients, and Sjögren syndrome.
Radiation-induced xerostomia (Dry mouth)
Radiation therapy plays an important role in the treatment of many types of oral cancer, alone or in combination with chemotherapy or surgery.
Ionising radiation, however, can cause alterations in the salivary glands, which are highly sensitive to radiation.
Radiation is one of the factors that produces the most severe xerostomia (Dry mouth). In the long term, it can end up destroying tissue and the ability to salivate.
Xerostomia (Dry mouth) Treatment with cultured mesenchymal stem cells
Treatment with expanded mesenchymal stem cells for xerostomia (Dry mouth) is focused on increasing the amount of salivary flow, recuperating the ability to salivate and the pleasure of eating.
At ITRT we are applying this innovative treatment in xerostomia (Dry mouth) patients in a clinical trial, obtaining promising results in the first patients treated, which are able to be maintained in the long term.
Up to now, the processes of bone marrow harvesting and cell inoculation, after the expansion process, have shown that they are safe methodologies, without evidence of adverse effects.
Xerostomia (Dry Mouth)
Stem cells to regenerate salivary glands damaged by radiation