Avascular Necrosis (Osteonecrosis)
A long-lasting solution for your bones
avascular necrosis (osteonecrosis)?
Osteonecrosis is a disease caused by the loss of blood flow inside the bones, or ischemia. Without blood flow the tissue dies (necrosis) and the bone weakens.
Osteonecrosis can be caused by a serious illness or trauma, such as a fracture or dislocation, which affects the blood flow to the bone. However, in other cases, it may occur without the cause being known (idiopathic osteonecrosis).
If osteonecrosis occurs near a joint, it can alter it and promote an earlier onset of osteoarthritis. Usually, the affected bones include the hip, shoulder, knee, elbow, wrist and ankle. At first, it does not usually cause any symptoms, but as the disease progresses the joint pain gets worse.
Avascular Necrosis (Osteonecrosis) of the femoral head
Osteonecrosis of the femoral head or hip usually affects people between the ages of 40 and 60.
Although it can be resolved without complication, most patients who progress to hip osteoarthritis will require prosthetic implantation.
Avascular Necrosis (Osteonecrosis) of the femoral head Treatment with cultured mesenchymal stem cells
Currently there are different treatments trying to prevent the progression of osteonecrosis. Perforation or forage of the femoral head and neck is a surgical intervention that has proven effective in the early stages for reducing pain and facilitating the formation of new blood vessels in necrotic tissue. However, for many patients, this intervention is not enough, and the disease may progress causing a collapse of the femoral head and osteoarthritis of the joint. In these cases, severe osteoarthritis can develop, requiring a hip prosthesis implant.
The cellular therapy we perform at ITRT consists of a perforation or forage in the femoral head, creating a tunnel where a biograft formed by mesenchymal stem cells and calcium biomaterial is implanted.
Our treatment has been shown to decrease the progression of osteonecrosis, as well as to prevent the collapse of the joint and, in many cases, the need of a prosthesis implantation.
8 out of 10 patients have evolved satisfactorily; their pain has disappeared and they have not required a prosthesis.
This treatment can only be performed in those cases in which the femoral head affected by osteonecrosis still retains its spherical anatomical shape.