Our therapy is based on 


because the scientific evidence

has shown that only by multiplying them

to reach millions of units, regeneration can be achieved


Avascular Necrosis

A permanent solution that regenerates bone and cartilage and makes prosthesis unnecessary

What is

Avascular Necrosis?

Avascular necrosis (AVN) is the death of bone tissue due to a loss of blood supply. You might also hear it called osteonecrosisaseptic necrosis, or ischemic bone necrosis.

If untreated, it can cause the bone to collapse. It most commonly affects the hip, but may also occur in shoulders, knees and ankles.

In its early stages, AVN usually has no symptoms. As the disease grows worse, it becomes painful. At first, pain may only arise if the affected bone is under pressure, but later it can become constant.

Collapse of the bone and surrounding joint can cause severe pain and inability to use the joint. The time that elapses between the initial symptoms and bone collapse can range from several months to more than a year.


Avascular Necrosis from
Femoral head (hip)

It can occur due to a variety of either traumatic or atraumatic causes that include fractures, dislocations, chronic steroid use, chronic alcohol use, coagulopathy, and may have congenital and many other causes. Only in the States, are reported from 10.000 to 20.000 new cases per year.

If untreated, the disorder can progress and require prosthesis implantation in most patients. At ITRT, we offer a definitive, permanent solution that prevents to implant a prosthesis.

Cultured Stem Cells to heal AVN of the femoral head

The cell therapy that we perform at ITRT consists of creating a tunnel to implant 80 million of cultured mesenchymal stem cells are implanted  in the hip. ITRT treatment has been shown to prevent joint collapse and the need to implant a prosthesis

This treatment can only be performed in cases in which the femoral head still retains its spherical anatomical shape.

ITRT Procedure of culturing of stem cells

Scientific Endorsement

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